Gut bacteria could be driving the problems of children with rare but critical food allergy conditions, a recent study says.
Children with food protein-induced enterocolitis syndrome (FPIES) have gut bacterial profiles that differ significantly from those of healthy children, the Umea University researchers noted in a report published on April 11, 2026. The report was published in the Journal of Allergy and Clinical Immunology.
FPIES occurs without the usual allergy antibodies, with key symptoms emerging more slowly and primarily impacting the GI tract rather than causing rashes or breathing problems. The condition begins during infancy and often leads to chronic vomiting, diarrhea, and circulatory problems.
In the new study, scientists compared stool samples from 56 children recently diagnosed with FPIES to those from 43 children without known allergies.
Take Control of Your Health Today
Quickly check your symptoms and understand your prescriptions with our smart, easy-to-use AI tools.
Distinct alterations in gut bacteria characterize FPIES. Scientists discovered that children with FPIES had reduced amounts of Bifidobacterium and Verrucomicrobiota, whereas bacteria such as Bacteroides, Haemophilus, and Veillonella were increased in abundance.
Additionally, scientists of the Children’s Hospital of Philadelphia reported that almost all food triggers were associated with lower levels of Verrucomicrobiota, namely corn, egg, fish, milk, peanut, and banana.
The gut microbiome composition changed as children grew older, yet the condition of FPIES was a separate factor contributing to gut bacteria independently of age, according to scientists. Bifidobacterium species play many positive roles in infant development – they facilitate the digestion of breast milk, improve gastrointestinal health, and stimulate immune system maturation, as scientists explained in their scientific paper.
Similarly, Verrucomicrobiota species are vital for maintaining intestinal epithelial integrity, which protects against allergen absorption, scientists stated. Over time, these findings may contribute to the development of more individualized strategies for diagnosis, prevention or treatment, although such applications will require further research.
For more interesting news and updates on food and recipes, follow Medipedia. We help you stay up to date on the latest news and developments in health, medication, and treatment practices.Â
Disclaimer:
This content is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting or changing any medication or treatment.