Patients with benign prostatic hyperplasia (BPH) with preoperative overactive bladder (OAB) have higher postoperative storage symptoms despite comparable overall symptom improvement, according to a review published online March 31, 2026, in the International Neurology Journal.
A systematic review was conducted on the results of endoscopic operations in patients with BPH complicated by OAB before surgery. Altogether, thirteen studies were reviewed, involving 1,436 cases – 672 and 820 in the OAB and no-OAB groups, respectively.
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It was discovered that storage symptoms-IPSS were higher in favor of the OAB group at six months postoperatively (MD, 1.06), but there were no differences noted in terms of changes observed three and six months later. In regard to total-IPSS, both groups had similar results three and six months after surgery; however, the no-OAB group achieved statistically significant improvement 12 months after surgery (MD, 3.66).
At three months, no statistically significant differences in the QoLI were reported, while at six months, holmium laser enucleation of the prostate proved superior for the OAB group (MD, -0.36); after six months, the change in outcomes favored the no-OAB group (MD, -0.61). There were no statistically significant differences regarding urge UI and PTA.
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